The major reason I picked out Newark is that it is a MAJOR airport. I would similarly recommend Philadelphia and (godforbid) JFK. Flying to major airports tends to be cheaper and can usually be done without a layover. Also, as Scott mentioned, a lot of people come from that area of New Jersey (or drive near it). That said, if he can get a good flight to Wilkes-Barre, more power to him.
Oh, and for the record, Jess apparently hasn't driven to Pittsburgh any time recently. The trip from here to the site is 5-6 hours, depending on traffic. And, last I checked, I am the only making that trip regularly.
-MS